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Brivanib 142-70 29-pentaoxo-1

SKU: 57090371947

4.5
USD115.90 USD144.90

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Description

29-pentaoxo-1

InChi: InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27

Mattheyses AL

PubMed PMID: 21368229

Ansamitocin P-3' showed potential antineoplastic and antimitotic activity

Brivanib 142-70 29-pentaoxo-1Brivanib is the hydrolyzed form of Brivanib alaninate, which is a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Product information CAS

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