Isoginkgetin ker Conjugates 3 Solubility: H2O : 50 mg/mL

Solubility: H2O : 50 mg/mL (480

Indoline dye D149

WO2018206635A1

Smiles: CC(O)=C(C#N)C(=O)NC1=CC(Br)=CC=C1Br

Pharmacother

Isoginkgetin ker Conjugates 3 Solubility: H2O : 50 mg/mLIsoginkgetin is a MMP 9 inhibitor, also a Pre mRNA Splicing Inhibitor with IC 50 of 30 uM. target : MMP 9 , Pre mRNA Splicing IC 50: 30 u M (Pre mRNA Splicing)In vitro: Isoginkgetin inhibits HT1080 tumor cell invasion substantially. Isoginkgetin is also quite effective in inhibiting the activities of Akt and MMP 9 in MDA MB 231 breast carcinomas and B16F10 melanoma. Isoginkgetin treatment result in marked decrease in invasion of these cells.