AUNP-12 - CAS# 1353563-85-5 11046 Cell culture growth inhibition by

Cell culture growth inhibition by GSK461364 can be cytostatic or cytotoxic but leads to tumor regression in xenograft tumor models under proper dose scheduling

88 mumol/L on RET kinase

2016 Dec 6

PubMed PMID: 26561057

Chemical Name: N-(2-aminophenyl)-N'-phenyloctanediamide

AUNP-12 - CAS# 1353563-85-5 11046 Cell culture growth inhibition byAUNP 12 (NP 12) is a peptide antagonist of the PD 1 signaling pathway, displays equipotent antagonism toward PD L1 and PD L2 in rescue of lymphocyte proliferation and effector functions. AUNP 12 exhibits immune activation, excellent antitumor activity, and potential for better management of immune related adverse events (irAEs). Product information CAS Number: 1353563 85 5 Molecular Weight: 3261. 55 Formula: C142H226N40O48 Chemical Name: N2, N6 bis(L