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11(6):e0158322
Thiazovivin
Synthesis and biological evaluation of 9-oxo-9H-indeno[1
PubMed PMID: 22444253
1007/s40290-019-00288-x
Lazertinib Catalog No.:M13413-2 11(6):e0158322Lazertinib (YH25448,GNS 1480) is a potent, highly mutant selective and irreversible EGFR TKI with IC50 values of 1. 7 nM, 2 nM, 5 nM, 20. 6 nM and 76 nM for Del19 T790M, L858R T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4. Product information CAS Number: 1903008 80 9 Molecular Weight: 554. 64 Formula: C30H34N8O3 Chemical Name: N {5 [(4 {4 [(dimethylamino)methyl] 3 phenyl 1H pyrazol 1
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