(R)-Simurosertib 118 551 Hydrochloride 2R)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}methyl)carbamoyl]-2-hydroxypropyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-methylbutyl]butanediamide

2R)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}methyl)carbamoyl]-2-hydroxypropyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-methylbutyl]butanediamide

Solubility: DMSO : 250 mg/mL (780

2019 Dec 9

3-dihydro-1H-indol-2-one

CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus

(R)-Simurosertib 118 551 Hydrochloride 2R)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}methyl)carbamoyl]-2-hydroxypropyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-methylbutyl]butanediamide(R) Simurosertib ((R) TAK 931) is the (R) enantiomer of Simurosertib. Simurosertib (TAK 931) is an orally active, selective and ATP competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of <0. 3 nM . Product information CAS Number: 1330782 69 8 Molecular Weight: 341. 43 Formula: C17H19N5OS Chemical Name: 2 [(2R) 1 azabicyclo[2. 2. 2]octan 2 yl] 6 (5 methyl 1H pyrazol 4 yl) 3H,4H thieno[3,2 d]pyrimidin 4 one Smiles: